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CVE-2026-31972

samtools mpileup has use-after-free leading to an invalid read

Medium6.9EPSS 0.55%
Published
Updated
Reserved
Assigned by
GitHub_M

Description

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. The `mpileup` command outputs DNA sequences that have been aligned against a known reference. On each output line it writes the reference position, optionally the reference DNA base at that position (obtained from a separate file) and all of the DNA bases that aligned to that position. As the output is ordered by position, reference data that is no longer needed is discarded once it has been printed out. Under certain conditions the data could be discarded too early, leading to an attempt to read from a pointer to freed memory. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. This bug is fixed in versions 1.21.1 and 1.22. There is no workaround for this issue.

Scores

CVSS scores of CVE-2026-31972, by who scored it
Scored byCVSSScoreVector
GitHub_MCNA (assigner)4.0Medium6.9CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N
NVDNVD · Analyzed4.0Medium6.9CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
EPSS (exploitation in 30 days)
0.55% · top 54% of all CVEs (6 Nov 2026)
CISA SSVC
Exploitation: none · Automatable: yes · Technical impact: partial
Loading the EPSS history…

The list uses the assigner's score when there is one, then CISA's, then NVD's: Medium 6.9.

Weakness

Affected products

References (3)

Sources

The same CVE in the primary databases and aggregators, to check against.

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Record last updated .